Figure 1.
Model of K-Ras G12C bound to GDP (sticks). Cysteine 12 is located in the P-loop opposite the catalytic magnesium (magenta ball) and switches 1 (green) and 2 (pink). Model based on PDB: 4EPR.
Model of K-Ras G12C bound to GDP (sticks). Cysteine 12 is located in the P-loop opposite the catalytic magnesium (magenta ball) and switches 1 (green) and 2 (pink). Model based on PDB: 4EPR.