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((a), (b)) Visualase applicator tip used in initial clinical investigation of LITT in GBM patients [4]. (a) Fiber protection sheath. (b) Illuminated fiber tip, arrow notes magnetite particle coating used for visual reference during MR imaging [4]. (c) Most recent iteration of Visualase laser applicator, shown with cooling catheter attachment. (d) MR reference image showing the insertion of the entire length of the applicator [9].
