Table 1.
Preoperative demographic data, clinical characteristics and severity of coronary heart disease in 910 patients surviving two months after CABG
| |
DM–/MetS– |
DM–/MetS+ |
DM+ |
Overall |
|---|---|---|---|---|
| n = 375 | n = 279 | n = 256 | p-value | |
|
Female (%) |
15.2 |
26.2 |
23.8 |
<0.011,2 |
|
Mean Age (years) (SD) |
61.3 (8.2) |
60.7 (8.6) |
63.3 (8.4) |
<0.0012,3 |
|
Variables of Modified MetS | ||||
|
BMI (kg/ m
2
) |
25.8 |
28.7 |
28.1 |
NA |
|
Elevated Blood Pressure (%) |
40.9 |
83.1 |
67.5 |
|
|
HDL Cholesterol (low, %) |
44.9 |
90.2 |
65.3 |
|
|
Triglyceride (high, %) |
27.4 |
83.7 |
67.7 |
|
|
Elevated Glucose or DM (%) |
4.5 |
25.8 |
100.0 |
|
|
Concomitant Diseases | ||||
|
Hypercholesterolemia (%) |
69.5 |
80.3 |
77.7 |
NS |
|
Previous MI (%) |
70.5 |
67.8 |
67.7 |
NS |
|
Previous TIA or stroke (%) |
8.9 |
8.6 |
13.9 |
NS |
|
Intermittent Claudication (%) |
6.2 |
4.7 |
18.6 |
<0.0013,4 |
|
Renal Function | ||||
|
CreaCl (ml/min) (SD) |
76.4 (13.8) |
74.2 (18.2) |
73.7 (16.9) |
NS |
|
CreaCl < 60 ml/min/1,73 m
2
(%) |
11.0 |
19.0 |
19.7 |
<0.011,2 |
|
Preoperative Smoking (%) |
66.6 |
60.2 |
66.4 |
NS |
|
Severity of Heart Disease | ||||
|
EF (%) (SD) |
60 (14) |
61 (13) |
58 (14) |
<0.055 |
|
EF ≤ 35% (%) |
7 |
4 |
11 |
<0.055 |
|
NYHA II (%) |
11.9 |
13.0 |
6.5 |
|
|
NYHA III (%) |
59.9 |
54.3 |
56.3 |
<0.055 |
|
NYHA IV (%) |
28.2 |
32.6 |
37.2 |
|
|
Operation Characteristics | ||||
|
Three–vessel Disease (%) |
61.1 |
59.7 |
58.6 |
NS |
|
Left Main Disease (%) |
13.1 |
16.6 |
14.1 |
NS |
|
Number of Grafts |
3.39 |
3.38 |
3.35 |
NS |
|
Use of Arterial Grafts (%) |
86.3 |
83.4 |
81.0 |
NS |
|
Concomitant Operation (%) |
6.1 |
3.3 |
7.6 |
NS |
|
Perfusion Time (SD) |
107.0 (36.6) |
108.0 (58.8) |
112.3 (34.2) |
NS |
| Urgent or Emergency Operation (%) | 26.7 | 29.9 | 33.5 | NS |
Abbreviations: MI myocardial infarct, TIA transient ischemic attack, EF ejection fraction, NYHA angina pectoris symptoms according to New York Heart Association, CHD coronary heart disease, LM left main, low HDL cholesterol: men < 1.03 mmol/l, women < 1.3 mmol/l, elevated triglycerides: ≥ 1.7 mmol/l, NS = not significant, NA = not applicable.
1Unadjusted p < 0.01 by the pooled t-test for the comparison DM-/MetS+ against DM-/MetS-.
2Unadjusted p < 0.01 by the pooled t-test for the comparison DM+ against DM-/MetS-.
3Unadjusted p < 0.001 by the pooled t-test for the comparison DM+ against DM-/MetS+.
4Unadjusted p < 0.001 by the pooled t-test for the comparison DM+ against DM-/MetS-.
5Unadjusted p < 0.05 by the pooled t-test for the comparison DM+ against other groups.