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. 2014 Jan 22;4:1. doi: 10.1186/2045-9912-4-1

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Copyright © 2014 Martin et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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NO uptake efficiency for pulsed and constant concentration delivery. Plotted with varying (a) tidal volume, (b) inspiratory time fraction, (c) breathing frequency, (d) functional residual capacity (FRC), (e) expiratory time constant, and (f) varying FRC together with tidal volume, where tidal volume is scaled in proportion to FRC. When not the varied parameter, the following values were used: FRC = 3000 ml, D_LNO = 150 ml/min/mm Hg, tidal volume = 500 ml, breath frequency = 12 min^-1, inspiratory time fraction = 1/3, and expiratory time constant = 0.6 s.