Table 2.
Univariate and backwards stepwise regression analyses of percentage change in renal medullary tissue oxygenation (T2* signal intensity) in response to a 20 mg intravenous furosemide stimulus
| Variables |
Univariate |
Backwards stepwise regression |
||
|---|---|---|---|---|
| Parameter estimate (SE) | p-value | Parameter estimate (SE) | p-value | |
| Age |
0.32 (0.29) |
0.28 |
|
|
| Glomerular filtration rate |
0.05 (0.11) |
0.65 |
|
|
| Gender |
2.27 (4.31) |
0.61 |
|
|
| Ethnicity |
-14.4 (4.61) |
0.006* |
-13.1 (4.09) |
0.004* |
| Stenosis severity (%) |
-0.12 (0.06) |
0.04* |
-0.11 (0.05) |
0.04* |
| Diabetes diagnosis |
0.72 (4.61) |
0.88 |
|
|
| Body mass index |
-0.49 (0.33) |
0.15 |
|
|
| Chronic daily furosemide dose (mg/day) |
-0.09 (0.05) |
0.09 |
-0.11 (0.04) |
0.01* |
| ACEI/ARB use |
6.41 (4.64) |
0.18 |
|
|
| Antihypertensive medications (number) | 0.98 (1.74) | 0.58 | ||