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Merlin knockout animals show altered myelination. (A) Schematic diagram indicating important nerve fibre parameters. (B and C) Myelination thickness and g-ratio quantifications of sciatic nerves taken from (B) merlin isoform-specific knockout animals (iso1 -/-; iso2 -/-) and wild-type littermates (iso1 +/+; iso2 +/+) as well as from (C) P0-Cre;Nf2flox mice bearing a Schwann cell-specific merlin loss (data represent mean ± SEM; **P < 0.01; ***P < 0.001; n > 300).
