Figure 7.

Effect of DEC on immunohistochemical localization of COX-2 in lung tissue after pleurisy induced by carrageenan. (a) In tissue sections from the CAR group, positive labeling was detected on type II pneumocytes. (b) Treatment with DEC significantly reduced COX-2 staining in comparison to the CAR group, achieving levels similar to the sham group. (c) Densitometry analysis of immunohistochemistry photographs for COX-2 from lung tissues; figure is representative of at least 3 experiments performed on different experimental days; data expressed as mean ± S.E.M. from n = 5 mice for each group; ND: not detected; *P < 0.05 versus carrageenan; scale bar = 20 μm.