Table 1.
Treatment | Before Treatment | After Treatment | |||
---|---|---|---|---|---|
WKY | SHR | WKY | SHR | ||
Sham | Vehicle | 156 ± 7 | 209 ± 6* | 144 ± 9 | 213 ± 3* |
CCI | Vehicle | 145 ± 6 | 220 ± 8* | 149 ± 13 | 232 ± 16* |
CCI | (+/−)-Thioctic acid 250 μmol/Kg/day | 157 ± 9 | 198 ± 8* | 155 ± 8 | 207 ± 5* |
CCI | (+/−)-Thioctic acid 125 μmol/Kg/day | 149 ± 11 | 208 ± 12* | 150 ± 14 | 205 ± 9* |
CCI | (+)-Thioctic acid 125 μmol/Kg/day | 148 ± 6 | 211 ± 11* | 136 ± 13 | 225 ± 8* |
CCI | (−)-Thioctic acid 125 μmol/Kg/day | 154 ± 4 | 201 ± 14* | 156 ± 9 | 217 ± 9* |
CCI | Pregabalin 300 μmol/Kg/day | 150 ± 6 | 215 ± 5* | 146 ± 5 | 201 ± 9* |
The data are expressed as mmHg and are the mean of 3 different measurements. *P < 0.01 versus WKY rats of the same group of treatment.