Figure 1.

Organ colonization from high dose orally infected mice. Graphs (A–D) (A, Intestine; B, Mesenteric lymph node; C, Liver; D, Spleen) depict CFU/g obtained from plating serial dilutions of homogenized organs (intestines, mesenteric lymph node, liver and spleen) from mice orally infected with two consecutive doses of 10⁹ CFU of M. avium subsp. paratuberculosis K10 over a 24 week period. Each dot represents one mouse, the hash mark denotes the mean, and the dotted line represents the minimum detection limit. (^*p < 0.05).