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. Author manuscript; available in PMC: 2014 Feb 5.
Published in final edited form as: Adv Drug Deliv Rev. 2012 Dec 1;64(Suppl):353–365. doi: 10.1016/j.addr.2012.09.011

Fig. 8.

Fig. 8

Role of binding in the interstitial transport in tumors, measured using fluorescence recovery after photobleaching. (a) Recovery of a photobleached spot is complete in about 100 s for a non-specific monoclonal antibody. (b) Recovery is incomplete for an antibody against carcino-embryonic antigen, present on the surface of many carcinoma cells (adapted from Ref. [94]).