Skip to main content
. 2013 Nov 19;17(12):1525–1536. doi: 10.1111/jcmm.12177

Figure 6.

Figure 6

(A–G) Affected ileal specimens from Crohn’s disease (CD) patients. (A) Masson’s trichrome staining. (B–G) Immunoperoxidase labelling for α-smooth muscle actin (α-SMA) (B and G) and CD34 (C–F) with haematoxylin counterstain. (A) At the border with the subserosa, longitudinal muscle bundles are separated by inflammatory infiltrate and fibrous connective tissue. In consecutive immunostained sections, many α-SMA-positive myofibroblasts are visible (B) while CD34-positive telocytes (TC) are absent (C). (D and E) In areas of the subserosa displaying inflammatory infiltration and incoming fibrosis, TC are not visible around vessels (D), but they are still present around nerves (E). (F and G) In areas of the subserosa with settled fibrosis, TC are rare or completely absent (F), while numerous α-SMA-positive myofibroblasts are observed (G). LM: longitudinal muscle layer; LV: lymphatic vessel; S: subserosa. Scale bars are indicated in each panel.