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. 2013 Nov 19;17(12):1525–1536. doi: 10.1111/jcmm.12177

Figure 7.

Figure 7

(A–C) Control ileal specimens. (D–F) Affected ileal specimens from Crohn’s disease (CD) patients. (A–F) Double immunofluorescence labelling for CD34 (green) and platelet-derived growth factor receptor α (PDGFRα) (red). In the ileal wall, all CD34-positive telocytes (TC) are also PDGFRα-positive. (A–C) In control specimens, TC form a broad network surrounding the myenteric plexus. (D–F) In severely damaged areas of affected CD specimens, the TC network around the myenteric plexus is discontinuous or even absent. MP: myenteric plexus. Scale bars are indicated.