Table 2.

Functions of major microRNA in chondrogenesis

Name	Types of chondrogenesis	Targets	Function	Reference
miR-34a	Prenatal	RhoA/Rac1	Rearrange actin cytoskeleton	25
		EphA5	Inhibit chondroblast migration	26
miR-142-3p	Prenatal	Adam9	Limb type-specific chondrogenesis	28
miR-375	Prenatal	Cadherin-7	Inhibit pre-cartilage condensation	29
miR-221	Prenatal	Mdm2	Promote progenitor proliferation	30
miR-455-3p	Prenatal	ACVR2B, SMAD2, CHRDL1	Affect TGFβ Signalling	21
miR-449a	Postnatal	LEF-1	Delayed Chondrogenesis	43
miR-23b	Postnatal	PKA signalling	Promote chondrogenic differentiation	44
miR-145	Postnatal	Sox9	Affect chondrogenic differentiation	45
miR-199a*	Postnatal	Smad1	Decrease chondrogenic marker genes	46
miR-194	Postnatal	Sox5	Inhibit chondrogenic differentiation	53