Table 1.

Description of three subtypes characterised by GGIs

Subtypes	Regional distribution of oligodendroglial inclusions	GOIs	CBs	GAIs	AHC	Clinical features	Common clinical diagnoses	Previous reports
Type I	FT	+++	+	+	-	FLF and/or Dem	FTD, PiD	[1-3, 6, 10, 13, 18, 21]
Type II	MTR and/or CST	++	++	+	±	FLF, PF and/or EPF	PSP, CBS, MND, PLS	[1, 12]
Type III	FT, MTR and/or CST	++	++	+++	++	FLF, Dem, MND and/or EPF	PSP, CBS, MND	[7, 20]

GOIs globular oligodendroglial inclusions, CBs coiled body-type inclusions, GAIs globular astrocytic inclusion, AHC anterior horn cell involvement (neuronal loss and tau pathology), FT frontotemporal, FLF frontal-lobe features, Dem dementia, FTD frontotemporal dementia, PiD Pick's disease, MTR motor cortex, CST corticospinal tract, PF pyramidal features, EPF extrapyramidal features, PSP progressive supranuclear palsy, CBS corticobasal syndrome, PLS primary lateral sclerosis, MND motor neuron disease features, - negative/absent, + low severity, ++ moderate severity, +++ high severity