Fig. 2.—

Cross-population phylogeny of the PaLoc. Phylogenies constructed from the catalytic and protease domains of tcdB (A), from the translocation and receptor binding domains of tcdB (B), and from the catalytic, protease, and part of the translocation domain of tcdA (C). Breaks in assembly caused by repetitive sequences in the receptor-binding domain of tcdA precluded its inclusion. Colored shapes indicate clade as in figure 1. Strain labels and bootstrap values are shown in supplementary figure S2, Supplementary Material online.