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. Author manuscript; available in PMC: 2014 Feb 5.
Published in final edited form as: Science. 2012 Jan 20;335(6066):319–324. doi: 10.1126/science.1214824

Figure 1.

Figure 1

(A) Schematic diagram of the single lysozyme being interrogated by a carbon nanocircuit. The partial PMMA coating is depicted in gr a y. (B) AFM topography of a SWNT FET before (inset) and after coating with the pyrene linker, lysozyme incubation, and washing to reduce nonspecifi c binding. The c ircle highlights the point of lysozyme attachment. (C) Response of current in a lysozyme device to electrolytic gating. (D) I (t) measured in phosphate buffer, with peptidoglycan substrate (25 μg/ml) added to the solution at t = 0. The ins et with a magnified time axis indicates a rapid response of <50 ms (inset).