Table 5. Summary of previous studies in which the relation between LV geometry and clinical events was examined in dialysis patients.
Author | patient nr | LV measurement | event | Risk measure | Conclusion |
Silverberg et al | 133 | LVMi (g/m2) | mortality | RR: 2.9 (p = 0.013) | LVH is an important determinant of survival |
1989 (33) | CV mortality | RR: 2.7 (0.08) | in incident dialysis patients | ||
Foley et al | 433 | LVMi (g/m2) | mortality | RR: 1.003 (p = 0.11) | LVH is highly prevalent in th dialysis |
1995 (2) | late (>2 yr) mortality | RR: 1.009 (p<0.001) | population and is a risk factor for mortality | ||
London et al | 153 | more than 10% decrease | mortality | RR: 0.78 (p = 0.001) | partial regression of LVM has a favorable |
2001 (4) | in LVMi (g/height2.7) | CV mortality | RR: 0.72 (p = 0.002) | effect on mortlity and CV-mortality | |
Zoccali et al | 254 | LVMi (g/m2) | mortality | HR: 1.01 (p<0.001)/1.03 (p<0.001) | LVM indexed for height2.7 provides a more |
2001 (32) | LVMi (g/height2.7) | CV mortality | HR: 1.01 (p<0.001)/1.03 (p<0.001) | powerful predictor for death and CV events | |
CV event | HR: 1.00 (ns)/1.02 (p = 0.004) | compared to LVM indexed for BSA | |||
Zoccali et al | 161 | in top 75% progression | mortality | HR: 3.07 (p = 0.008) | Changes in LVMi have an independent |
2004 (3) | in LVMi (g/height2.7) | CV event | HR: 3.02 (p = 0.02) | prognostic value for death and CV events |
CV events are defined as a combination of both fatal and non-fatal cardiovascular events.
BSA: body surface area; CV: cardiovascular; HR: hazard ratio; LV: left ventricular; LVH: left ventricular hypertrophy; LVM: left ventricular mass; LVMi: left ventricular mass index; nr: number; RR: relative risk.