Table 1. BAL proteome flux in a non-lethal mouse model of influenza infection.
BAL Protein | Swissprot | No.of | Fold Change over Day-0 | Cluster | ||
Accession | peptides | Day-5 | Day-14 | Day-21 | Group* | |
Serum albumin | P07724 | 31 | 5.32 | 6.79 | 4.41 | 4 |
Serotransferrin | Q921I1 | 28 | 7.22 | 11.41 | 8.48 | 4 |
Complement C3 | P01027 | 28 | 3.83 | 3.07 | 1.65 | 4 |
Hemopexin | Q91X72 | 16 | 3.34 | 5.54 | 2.16 | 4 |
Alpha-2-macroglobulin | Q61838 | 14 | 5.72 | 5.34 | 2.45 | 4 |
Ceruloplasmin | Q61147 | 14 | 2.65 | 4.45 | 2.45 | 4 |
Vitamin D-binding protein | P21614 | 12 | 4.34 | 5.12 | 2.48 | 4 |
Apolipoprotein A-IV | P06728 | 10 | 2.79 | 4.47 | 2.58 | 4 |
Liver carboxylesterase N | P23953 | 9 | 2.18 | 3.16 | 1.94 | 4 |
Fibronectin | P11276 | 9 | 2.41 | 6.95 | 4.77 | 2 |
Apolipoprotein A-I | Q00623 | 8 | 4.03 | 4.57 | 2.47 | 4 |
Haptoglobin | Q61646 | 8 | 26.86 | 4.24 | 9.09 | 1 |
Kininogen-1 | O08677 | 7 | 3.2 | 4.85 | 2.8 | 4 |
Antithrombin-III | P32261 | 7 | 1.93 | 3.21 | 2.21 | 4 |
Hemoglobin subunit alpha | P01942 | 5 | 0.81 | 4.93 | 1.14 | 2 |
Beta-2-glycoprotein 1 | Q01339 | 6 | 3.77 | 6.13 | 3.07 | 4 |
Chitinase-3-like protein 3 | Q35744 | 6 | 0.48 | 0.49 | 1.45 | 3 |
Murinoglobulin-1 | P28665 | 5 | 4.3 | 4.9 | 2.46 | 4 |
Gelsolin | P13020 | 5 | 2.03 | 14.11 | 4.47 | 2 |
Actin, cytoplasmic 2 | P63260 | 6 | 3.67 | 3.15 | 1.36 | 4 |
Alpha-2-HS-glycoprotein | P29699 | 5 | 2.25 | 3.07 | 1.87 | 4 |
Hemoglobin subunit beta-1 | P02088 | 4 | 0.92 | 5.07 | 1.74 | 2 |
Clusterin | Q06890 | 4 | 3.55 | 3.55 | 2.29 | 4 |
Plasminogen | P20918 | 4 | 2.97 | 3.45 | 3.1 | 4 |
Pulmonary surfactant-associated protein D | P50404 | 4 | 0.6 | 0.55 | 1.2 | 3 |
Uteroglobin | Q06318 | 3 | 0.2 | 0.13 | 0.4 | 3 |
Chitinase-3-like protein 1 | Q61362 | 3 | 22.03 | 11.23 | 5.2 | 1 |
Pulmonary surfactant-associated protein B | P50405 | 3 | 0.56 | 0.3 | 0.49 | 3 |
Afamin | Q89020 | 3 | 2.56 | 4.43 | 2.13 | 4 |
Fibrinogen beta chain | Q8K0E8 | 3 | 5.87 | 4.6 | 1.68 | 1 |
Complement factor B | P04186 | 3 | 3.52 | 3.54 | 2.25 | 4 |
Glutathione S-transferase omega-1 | P78417 | 3 | 0.23 | 0.27 | 0.91 | 3 |
Apolipoprotein E | P08226 | 3 | 1.78 | 6.24 | 3.45 | 2 |
Lysozyme C-2 | P08905 | 3 | 0.53 | 0.41 | 0.77 | 3 |
Complement C4-B | P01029 | 3 | 3.6 | 2.63 | 1.63 | 1 |
Selenium-binding protein 2 | Q63836 | 3 | 0.54 | 0.57 | 0.76 | 3 |
Complement factor H | P06909 | 3 | 4.33 | 9.32 | 1.7 | 2 |
Vomeromodulin | Q80X17 | 2 | 0.56 | 1.2 | 4.29 | 3 |
Fetuin-B | Q9QXC1 | 2 | 1.63 | 3.73 | 1.19 | 2 |
Inter-alpha-trypsin inhibitor heavy chain | Q61703 | 2 | 2.45 | 4.31 | 1.85 | 4 |
Lactotransferrin | P08071 | 2 | 3.09 | 1.69 | 2.09 | 1 |
Pulmonary surfactant-associated protein A | P35242 | 2 | 0.49 | 0.29 | 0.59 | 3 |
Cluster grouping based on K-means clustering described in methods. # Days post infection.: