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. 2014 Feb 5;9(2):e86912. doi: 10.1371/journal.pone.0086912

Table 1. BAL proteome flux in a non-lethal mouse model of influenza infection.

BAL Protein Swissprot No.of Fold Change over Day-0 Cluster
Accession peptides Day-5 Day-14 Day-21 Group*
Serum albumin P07724 31 5.32 6.79 4.41 4
Serotransferrin Q921I1 28 7.22 11.41 8.48 4
Complement C3 P01027 28 3.83 3.07 1.65 4
Hemopexin Q91X72 16 3.34 5.54 2.16 4
Alpha-2-macroglobulin Q61838 14 5.72 5.34 2.45 4
Ceruloplasmin Q61147 14 2.65 4.45 2.45 4
Vitamin D-binding protein P21614 12 4.34 5.12 2.48 4
Apolipoprotein A-IV P06728 10 2.79 4.47 2.58 4
Liver carboxylesterase N P23953 9 2.18 3.16 1.94 4
Fibronectin P11276 9 2.41 6.95 4.77 2
Apolipoprotein A-I Q00623 8 4.03 4.57 2.47 4
Haptoglobin Q61646 8 26.86 4.24 9.09 1
Kininogen-1 O08677 7 3.2 4.85 2.8 4
Antithrombin-III P32261 7 1.93 3.21 2.21 4
Hemoglobin subunit alpha P01942 5 0.81 4.93 1.14 2
Beta-2-glycoprotein 1 Q01339 6 3.77 6.13 3.07 4
Chitinase-3-like protein 3 Q35744 6 0.48 0.49 1.45 3
Murinoglobulin-1 P28665 5 4.3 4.9 2.46 4
Gelsolin P13020 5 2.03 14.11 4.47 2
Actin, cytoplasmic 2 P63260 6 3.67 3.15 1.36 4
Alpha-2-HS-glycoprotein P29699 5 2.25 3.07 1.87 4
Hemoglobin subunit beta-1 P02088 4 0.92 5.07 1.74 2
Clusterin Q06890 4 3.55 3.55 2.29 4
Plasminogen P20918 4 2.97 3.45 3.1 4
Pulmonary surfactant-associated protein D P50404 4 0.6 0.55 1.2 3
Uteroglobin Q06318 3 0.2 0.13 0.4 3
Chitinase-3-like protein 1 Q61362 3 22.03 11.23 5.2 1
Pulmonary surfactant-associated protein B P50405 3 0.56 0.3 0.49 3
Afamin Q89020 3 2.56 4.43 2.13 4
Fibrinogen beta chain Q8K0E8 3 5.87 4.6 1.68 1
Complement factor B P04186 3 3.52 3.54 2.25 4
Glutathione S-transferase omega-1 P78417 3 0.23 0.27 0.91 3
Apolipoprotein E P08226 3 1.78 6.24 3.45 2
Lysozyme C-2 P08905 3 0.53 0.41 0.77 3
Complement C4-B P01029 3 3.6 2.63 1.63 1
Selenium-binding protein 2 Q63836 3 0.54 0.57 0.76 3
Complement factor H P06909 3 4.33 9.32 1.7 2
Vomeromodulin Q80X17 2 0.56 1.2 4.29 3
Fetuin-B Q9QXC1 2 1.63 3.73 1.19 2
Inter-alpha-trypsin inhibitor heavy chain Q61703 2 2.45 4.31 1.85 4
Lactotransferrin P08071 2 3.09 1.69 2.09 1
Pulmonary surfactant-associated protein A P35242 2 0.49 0.29 0.59 3
*

Cluster grouping based on K-means clustering described in methods. # Days post infection.: