Table 1. Differential regulation of Rab7 in tumor biopsy specimens by microarray analysis.

Differential Rab7 Expression Levels Reported in the ONCOMINE Database (Prostate Cancer)
Type of Analysis	Fold Change	P value	Reference	Sample Notes
PCa vs. Normal Prostate	−2.501	<0.0001	[41]	Samples contained 90% cancerous epithelial cells
PIN Epithelia vs. Normal Prostate	−1.939	0.013	[40]	Enriched for PIN epithelial cells
PCa Epithelia vs. Normal Prostate	−1.743	0.013	[40]	Enriched for cancerous epithelial cells
PCa vs. Normal Prostate	−1.265	<0.001	[42]	Pooled tumor samples–contained stromal cells
PCa vs. Normal Prostate	−1.118	0.003	[43]	Stromal cells included (not enriched for epithelial cells)
PCa vs. Normal Prostate	1.285	0.016	[43]	Stromal cells included (not enriched for epithelial cells)
PCa vs. Normal Prostate	−1.128	0.024	[44]	Stromal cells included (not enriched for epithelial cells)
PCa vs. Normal Prostate	1.294	0.004	[44]	Stromal cells included (not enriched for epithelial cells)
PCa vs. Normal Prostate	−1.012	0.32	[45]	Stromal cells included (not enriched for epithelial cells)
BPH Epithelia vs. Normal Prostate	−1.165	0.35	[40]	Benign epithelia
BPH Stroma vs. Normal Prostate	−1.118	0.039	[40]	Benign stroma

The ONCOMINE database was searched for differential expression of Rab7A mRNA in prostate cancer.