Table 2. Susceptibility of non-tuberculosis mycobacteria.
Minimum Inhibitory Concentration (µg/mL) | |||||
Compound | a M. abscessus | a M. avium | a M. kansasii | a M. fortuitum | b M. ulcerans |
9a | 12.50 | 200 | 3.13–6.25 | 6.25–12.50 | 0.02–0.05 |
Amikacin | 3.13–6.25 | 12.5 | 6.25–12.5 | 0.78 | ND |
Rifampin | 50.00 | 6.3 | 0.39 | 1.56 | 0.1–0.4 |
PA-824 | >200 | >200 | 3.1–12.5 | >200 | 3.1–25 |
Susceptibility of non-tuberculosis mycobacteria to nitrofurans and reference drugs.
MICs determined by macrobroth dilution and visual inspection of plates.
MIC determined by agar proportion method. Values reported are the range of at least two biologically independent experiments. Species tested included M. abscessus (ATCC 19977); M. avium (ATCC 25291); M. kansasii (ATCC 12478); M. fortuitum (ATCC 6841); and M. ulcerans (ATCC 35840).