Table 1. Synaptic and membrane properties of BS-cells in the subiculum before and after application of 5-HT4 receptor ligands.
RS 67333 (10 µM) | RS 39604 (25 µM) | |||
EPSP (% of Baseline) | 102.0±8.3 (n = 7, p = 0.85) | 93.1±8.0 (n = 6, p = 0.48) | ||
Baseline | Wash-in | Baseline | Wash-in | |
Rise-time (ms) | 3.4±0.4 | 3.3±0.4 | 3.8±0.6 | 3.5±0.5 |
(n = 6, p = 0.54) | (n = 4, p = 0.26) | |||
Decay-time (ms) | 10.9±1.3 | 11.0±1.4 | 14.5±1.6 | 14.1±1.4 |
(n = 6, p = 0.79) | (n = 5, p = 0.42) | |||
RMP (mV) | −73.0±3.1 | −73.4±3.7 | −64.6±1.6 | −65.6±2.0 |
(n = 5, p = 0.83) | (n = 6, p = 0.12) | |||
Rin (MΩ) | 29.7±6.4 | 30.6±7.6 | 40.6±2.5 | 39.2±3.5 |
(n = 5, p = 0.67) | (n = 6, p = 0.44) |
Data given as means ± SEM.