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. 2014 Feb 5;9(2):e88245. doi: 10.1371/journal.pone.0088245

Figure 5. Peptide B-specific antibodies picked 8-weeks post immunization and were significantly stimulated 4 weeks post-tick infection.

Figure 5

(A) IgG antibodies specific to Peptide B (open bars) and B. burgdorferi (grey bars) at weeks 0, 4, 8, and 12 post-priming. (B) IgG antibodies specific to Peptide D (open bars) and B. burgdorferi (grey bars) at weeks 0, 4, 8, and 12 post-priming. IgG (C) and IgM (D) antibody levels specific to each of the BB0172 peptide (open bars) and B. burgdorferi (gray bars) in control and animals immunized with either Peptide B or D 4-weeks post tick infection. (E) IgG1 and IgG2b antibody levels after 4, 8, 12 and 16 weeks post-priming with pepB. Titer represented in parenthesis. * Denotes statistically significant differences (* P value <0.05; ** P value < 0.01; *** P value < 0.001) when compared with the control group.