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. 2014 Feb 5;9(2):e88245. doi: 10.1371/journal.pone.0088245

Figure 7. Peptide B-specific antibodies confer protection against B. burgdorferi infection.

Figure 7

Antibody titers of control, peptide B-immunized, and peptide D-immunized animals. Open bars represent the anti-B. burgdorferi titers and black bars represent the peptide-specific antibody titers in each group (A). Bacterial recuperation from tissues of animals infected after passively transferring peptide specific serum (B) or splenocytes (C) to naïve mice. Bacterial burden was evaluated by qPCR in skin (D), spleen (E), lymph nodes (F), and joints (G). Bacterial recuperation from tissues and quantification was done 21 days-post infection. * Denotes statistically significant differences (* P value <0.05; ** P value < 0.01) when compared within the passive transfer treatment, while a (P value <0.05) and b (P value < 0.01) denote significant differences in between animals receiving serum or splenocytes from the same treatment (peptide B or peptide D).