Figure 4. Preference and activity patterns for different eccentricities in lower visual areas for the JMD patient.

(A) The medial view of the posterior part of right and left hemisphere is shown on an inflated cortical surface. The approximate location of the calcarine sulcus is marked with a dotted line. The color legend is shown above (orange-red for central stimuli, green for paracentral stimuli, blue-purple for peripheral stimuli) and reflects the relative preference to the different eccentricities. In black two regions are marked which are further characterized for illustration purposes. The data of one region (red arrow/box) are mostly dominated by a positive response, and for the other region (blue arrow/box) mostly by a negative response compared to a no-stimulus baseline (B) Activity patterns in both hemispheres compared to a fixation baseline, at p<0.05 uncorrected for one of three conditions: central (8 most central stimuli, contrasted against baseline), paracentral (8 paracentral stimuli, contrasted against baseline) and peripheral (8 most eccentric stimuli, contrasted against baseline). The selected ROIs now show the underlying positive and negative responses. (C) Time course averaged across runs and across stimulus sequences to represent the response in a selected ROI to different eccentricities. The red dotted lines represent the 95% confidence intervals (calculated using the variation across runs). (C, left panel) ROI with a small positive response to peripheral stimuli compared to a fixation baseline and negative responses to the other conditions (C, right panel) ROI with a close to zero response to central stimuli and negative responses to the other conditions.(D) Average beta values in each selected ROI. The left panel indicates activity of a ROI that shows a small positive response to the (visible) peripheral stimuli, while the right panel shows a ROI with negative responses to unstimulated parts of the visual field and the absence of activation in the central condition.