Table 2. Differentially-expressed major candidate genes detected in microarray related to PIA QTL.
Genes | Chromosomes | AIRmax/ AIRmin ratio | GO Biological process |
Slc11a1 | 1 | 2.98 | Transport |
Cxcl1 | 5 | 3.78 | Chemokine |
Cxcl9 | 5 | 2.67 | Chemokine |
Cxcl5 | 5 | 12.11 | Chemokine |
Cxcl13 | 5 | 27.50 | Chemokine |
Saa3 | 7 | 21.39 | Inflammation |
Il21r | 7 | 2.82 | Inflammation |
Bcl3 | 7 | 2.03 | Apoptosis |
Msr1 | 8 | 5.02 | Scavenger |
Hmox1 | 8 | 2.05 | Angiogenesis/apoptosis |
H2ea | 17 | 0.03 | Antigen Presentation |
Slc15a3 | 19 | 2.55 | Transport |
Differentially expressed genes in AIRmax and AIRmin mice. Mouse Gene 1.0 ST Array was used. Differentially expressed genes were detected using Significance of Analysis of Microarray (SAM) software (Two class unpaired, FDR ≤5%) that examined the data from four biological replicates on each line.