Table 7. Measures of albuminuria according to quintile of bone-specific alkaline phosphatase.

	Bone-specific ALP quintile (ug/L)
Model 1	<3.3	3.3-<3.6	3.6-<3.9	3.9-<4.2	≥4.2
uAlb	1	1.18 (1.05, 1.32) p = 0.004	1.15 (1.04, 1.29) p = 0.013	1.22 (1.09, 1.36) p<0.001	1.46 (1.30, 1.64) p<0.001
uCr	1	1.11 (1.02, 1.19) p = 0.014	1.11 (1.03, 1.21) p = 0.007	1.14 (1.05, 1.24) p = 0.001	1.14 (1.05, 1.23) p = 0.001
ACR	1	1.07 (0.99, 1.16) p = 0.086	1.03 (0.96, 1.12) p = 0.40	1.07 (0.98, 1.16) p = 0.13	1.29 (1.18, 1.40) p<0.001
FEalb	1	1.06 (0.98, 1.14) p = 0.15	1.01 (0.93, 1.09) p = 0.82	1.04 (0.96, 1.13) p = 0.29	1.24 (1.14, 1.35) p<0.001
Model 2
uAlb	1	1.14 (1.01, 1.27) p = 0.025	1.08 (0.97, 1.21) p = 0.17	1.12 (1.00, 1.26) p = 0.050	1.28 (1.14, 1.44) p<0.001
uCr	1	1.09 (1.01, 1.18) p = 0.024	1.09 (1.01, 1.18) p = 0.034	1.13 (1.04, 1.22) p = 0.002	1.14 (1.05, 1.23) p = 0.002
ACR	1	1.04 (0.96, 1.12) p = 0.84	0.99 (0.92, 1.08) p = 0.86	0.99 (0.92, 1.08) p = 0.84	1.13 (1.04, 1.23) p = 0.004
FEalb	1	1.03 (0.95, 1.11) p = 0.49	0.97 (0.89, 1.05) p = 0.39	0.97 (0.90, 1.06) p = 0.53	1.09 1.01, 1.19) p = 0.037
Model 3
uAlb	1	1.12 (1.01, 1.26) p = 0.038	1.07 (1.05, 1.19) p = 0.26	1.09 (1.02, 1.23) p = 0.12	1.24 (1.11, 1.40) p<0.001
uCr	1	1.09 (1.01, 1.18) p = 0.024	1.09 1.01, 1.18) 0.024	1.12 (1.04, 1.21) p = 0.004	1.14 (1.05, 1.23) p = 0.002
ACR	1	1.03 (0.95, 1.11) p = 0.45	0.97 0.90, 1.05) p = 0.50	0.98 (0.90, 1.06) p = 0.57	1.10 (1.01, 1.19) p = 0.035
FEalb	1	1.02 (0.95, 1.10) p = 0.55	0.96 (0.89, 1.04) p = 0.33	0.96 (0.88, 1.04) p = 0.30	1.07 (0.99, 1.17) p = 0.11

model 1: adjusted for age, gender and race.

model 2: as model 1 but additionally adjusted for BMI, weight, waist circumference, systolic and diastolic blood pressures, total:HDL cholesterol ratio, eGFR, diabetes status, HbA1c.

model 3: as model 2 but additionally adjusted for history of cardiovascular disease, poverty:income ratio, smoking status, CRP, hemoglobin, calcium.