Figure 5. The Type I interferon response to Neospora infection is dependent on Tlr3 and Trif.

QPCR analysis of Mx1 expression in Neospora infected bone marrow macrophages derived from wild-type (WT), Myd88^−/−, Myd88^−/−/Trif^−/−, Tlr2^−/−/Tlr4^−/− and Tlr3^−/− mice. Error bars indicate standard deviations for three biological replicates; * = P≤0.01. Experiment was repeated three times with similar results.