Figure 6.

Cell numbers in the piriform cortex are rescued as a result of glutamate (Glu) scavengers. (A, B) Example sections from paraoxon (PO) and OxAc+hGOT (human glutamate oxaloacetate transaminase) (A) and PO and saline (B) groups of hematoxylin and eosin (H&E) staining. Left and right columns represent left and right piriform cortex accordingly. (C) Example section of the piriform cortex from a naïve animal of H&E staining. All scale bars are 100 μm. (D) Quantification of cell densities per mm² from eight cortex sections of each group, each 6 μm width. Lower neuronal cell number indicates increased brain damage as a result of neuronal death. The amount of the rescued neurons is significantly higher in the OxAc+hGOT-treated group (n=8) as compared with the saline group (n=8), although the naïve group (n=5) had more neurons then both groups. *P<0.05, ***P<0.001. OxAc, oxaloacetate.