Table 3. Semi-quantitative perfusion valuesa in patients with DCI versus non-DCI.
| CTP time | Study | CTP performance | Subgroup | Median CBF ratio (range) | Median CBV ratio (range) | Median MTT difference (s) (range) | Median TTP difference (s) (range) |
|---|---|---|---|---|---|---|---|
| Admission | Van der Schaaf8 | <72 hours after ictus | DCI (n=16) | 0.61 (0.29–0.93) | 0.71 (0.46–0.88) | 1.35 (0.4–4.0) | 1.35 (0.3–3.5) |
| Non-DCI (n=30) | 0.81 (0.56–0.93) | 0.85 (0.47–0.98) | 0.70 (0.1–2.1) | 0.5 (0.1–2.8) | |||
| Clinical deterioration | Dankbaar6 | Clinical deterioration or 1 week after ictus (asymptomatic patients) | DCI (n=50) | 0.67 (0.00–0.86) | 0.74 (0.02–0.92) | 1.91 (0.68–57.7) | 1.34 (0.39–23.2) |
| Non-DCI (n=35) | 0.78 (0.27–0.91) | 0.82 (0.24–0.91) | 0.96 (0.35–3.2) | 0.70 (0.16–2.1) | |||
| Hickmann14 | Day 10 after ictus (delayed neurologic deterioration was mostly documented on day 10) | DCI (n=11) | 0.95 (0.79–0.98) | 0.94 (0.86–0.98) | NR | NRb | |
| Non-DCI (n=18) | 0.93 (0.73–0.99) | 0.94 (0.75–0.99) | NR | NRb |
CBF, cerebral blood flow; CBV, cerebral blood volume; CTP, CT perfusion; DCI, delayed cerebral ischemia; MTT, mean transit time; NR, not reported; s, seconds; TTP, time-to-peak.
a
Affected hemisphere compared with healthy hemisphere. Lowest CBF and CBV ratios and largest MTT and TTP differences were used.
b
Hickmann14 determined a TTP ratio instead of a TTP difference.