Figure 3.

Endothelial progenitor cells improve microvascular outcome after traumatic brain injury. (A) Representative images of rat endothelial cell antigen-1 (RECA-1)-labeled sections of the corpus callosum in sham, FPI+vehicle, and FPI+EPC-treated rats. (B) FPI+vehicle-treated rats had a significant reduction in mean capillary length relative to sham (*P=0.03). Although EPC treatment indicated a strong trend toward improvement relative to FPI+vehicle-treated rats, values were not statistically significant (P=0.075). (C) The total number of longitudinal capillaries in quantified sections were not significantly different thus validating the lack of bias in length quantification. (D) Red boxes indicate the fields used for RECA-1 quantification in the corpus callosum. (Scale bar, 50 μm) n=6 per treatment group.