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. 2014 Feb 6;8:49. doi: 10.3389/fnhum.2014.00049

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Copyright © 2014 Chang, Lee, Gu, Koo, Lee, Jin, Yeo, Seo and Jang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Four regions of interest based on the Brodmann area (BA) and anatomical location of areas of the brain. The primary sensory-motor cortex (SM1): BA 1, 2, 3, and 4; premotor cortex (PMC): BA 6 (BA 6, except for the SMA); supplementary motor area (SMA) (anterior boundary: vertical line to the anterior commissure, posterior boundary: anterior margin of M1, medial boundary: midline between the right and left hemispheres, lateral boundary: the line 15 mm lateral from the midline between the right and left hemispheres); prefrontal cortex (PFC): BA 8, 9, 44, 45, and 46. (B) Group-average activation map of HbO, HbR, and HbT during performance of passive movements of the right fingers, which were executed by the rehabilitation robotic hand using NIRS-SPM (uncorrected, p < 0.01).