Table 3. ADA and DPP-IV activity and sCD26 concentration in PE according to age groups in the study population (mean ± SD).
| ≤35 years old | 36–55 years old | ≥56 years old | ||
|---|---|---|---|---|
| ADA activity (UL−1) | Total | 131.3 ± 288.4 (19) | 43.9 ± 57.4 (32) | 45.1 ± 98.4 (86) |
| BPE | 68.0 ± 28.9 (17) | 50.2 ± 65.2 (24) | 70.1 ± 142.6 (39) | |
| +TPE | 78.4 ± 19.1 (14) | 63.6 ± 15.6 (7) | 79.5 ± 27.1 (9) | |
| +pneumonic* | 18.7 ± 7.6 (2) | 73.7 ± 130.1 (6) | 109.1 ± 241.5 (13) | |
| +paramalignant | 0 | 29.0 ± 4.0 (2) | 34.2 ± 0 (1) | |
| +non neoplastic | 0 | 26.1 ± 12.6 (5) | 42.6 ± 51.8 (10) | |
| +miscellaneous | 21.1 ± 0 (1) | 32.0 ± 22.5 (4) | 23.7 ± 7.0 (6) | |
| MPE | 669.5 ± 914.4 (2) | 25.1 ± 8.7 (8) | 24.3 ± 10.6 (47) | |
| +epithelial | 22.9 ± 0 (1) | 25.1 ± 8.7 (8) | 22.2 ± 7.0 (41) | |
| +mesothelioma | 0 | 0 | 34.4 ± 19.1 (5) | |
| +lymphoma | 1316.0 ± 0 (1) | 0 | 57.7 ± 0 (1) | |
| DPP-IV activity (UL−1) | Total | 43.7 ± 20.9 (21)‡ | 51.1 ± 26.2 (35)‡ | 43.6 ± 28.8 (91) |
| BPE | 41.0 ± 15.2 (19) | 47.1 ± 25.2 (26) | 39.2 ± 26.3 (42) | |
| +TPE | 39.8 ± 10.4 (14) | 38.3 ± 17.7 (7) | 31.1 ± 8.0 (9) | |
| +pneumonic* | 33.0 ± 5.0 (4) | 50.8 ± 26.1 (10) | 44.9 ± 28.2 (15) | |
| +paramalignant | 0 | 57.9 ± 0 (1) | 33.5 ± 0 (1) | |
| +non neoplastic | 0 | 57.2 ± 40.7 (6) | 32.0 ± 19.1 (11) | |
| +miscellaneous | 90.1 ± 0 (1) | 23.0 ± 4.1 (2) | 51.3 ± 45.8 (6) | |
| MPE | 69.6 ± 55.3 (2)∧ | 62.8 ± 26.8 (9)∧ | 47.4 ± 30.5 (49)∧ | |
| +epithelial | 30.5 ± 0 (1) | 62.8 ± 26.8 (9) | 44.5 ± 27.4 (44) | |
| +mesothelioma | 0 | 0 | 60.5 ± 42.7 (4) | |
| +lymphoma | 108.7 ± 0 (1) | 0 | 123.8 ± 0 (1) | |
| sCD26 concentration (μg L−1) | Total | 389.1 ± 128.6 (21) | 412.3 ± 148.2 (37)† | 357.4 ± 295.1 (101)† |
| BPE | 379.6 ± 123.5 (19) | 392.2 ± 158.3 (28)§ | 322.5 ± 136.3 (45)§ | |
| +TPE | 379.3 ± 112.3 (14) | 353.1 ± 60.6 (7) | 359.1 ± 151.2 (9) | |
| +pneumonic* | 367.3 ± 189.0 (4) | 377.4 ± 149.8 (10) | 352.3 ± 136.8 (15) | |
| +paramalignant | 0 | 491.4 ± 27.2 (2) | 422.0 ± 295.6 (2) | |
| +non neoplastic | 0 | 500.5 ± 134.0 (6) | 293.5 ± 108.2 (12) | |
| +miscellaneous | 432.9 ± 0 (1) | 414.4 ± 144.0 (3) | 232.6 ± 86.4 (7) | |
| MPE | 479.3 ± 195.0 (2) | 420.1 ± 205.7 (9) | 385.4 ± 376.4 (56) | |
| +epithelial | 341.4 ± 0 (1) | 420.1 ± 205.7 (9) | 316.3 ± 165.6 (48) | |
| +mesothelioma | 0 | 0 | 990.6 ± 897.6 (6) | |
| +lymphoma | 617.2 ±0 (1) | 0 | 226.9 ± 2.4 (2) |
In parentheses (n) number of samples. Significant differences between age groups: For DPP-IV;
‡U-Mann p = 0.007;
∧p = 0.013 and p = 0.003 respectively. For sCD26;
†p < 0.001 and
§p = 0.007.