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. 2013 Jul 23;1(5):845–850. doi: 10.3892/mco.2013.151

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Copyright © 2013, Spandidos Publications

This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.

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mRNA expression levels of heparan sulfate 6-O-sulfotransferase 2 (HS6ST2) in 10 paired colorectal cancer (CRC) and non-cancerous colonic mucosal samples and in various cancer cell lines. (A) Signal intensities of HS6ST2 were obtained from a microarray analysis. HS6ST2 was overexpressed in CRC (gray bars) compared to the paired mucosal samples (black bars) in almost all the patients. (B) The mRNA expression levels of HS6ST2 were assessed using quantitative reverse transcription-polymerase chain reaction in a panel of 83 cancer cell lines. Pt, patient number; Rel. mRNA, normalized mRNA expression levels (HS6ST2/GAPD × 10⁶); GC, gastric cancer; EC, esophageal cancer; PaC, pancreatic cancer; BC, breast cancer; HCC, hepatocellular carcinoma; ProC, prostate cancer; LC, lung cancer.