Table I.
Analysis of demographic and clinicopathological characteristics according to serum carcinoembryonic antigen (CEA) levels in patients with colorectal cancer.
| Characteristics | CEA | P-value for trend | |
|---|---|---|---|
|
| |||
| <7 ng/ml | ≥7 ng/ml | ||
| Gender | 0.438 | ||
| Female | 94 (41.4) | 34 (46.6) | |
| Male | 133 (58.6) | 39 (53.4) | |
| Age (years) | 0.881 | ||
| <60 | 119 (52.4) | 39 (53.4) | |
| ≥60 | 108 (47.6) | 34 (46.6) | |
| Radical operation | 0.223 | ||
| No | 33 (14.5) | 15 (20.5) | |
| Yes | 194 (85.5) | 58 (79.5) | |
| Blood transfusion | 0.029 | ||
| No | 178 (78.4) | 48 (65.8) | |
| Yes | 49 (21.6) | 25 (34.2) | |
| Histological type | 0.249 | ||
| Villous adenocarcinoma | 17 (7.5) | 5 (6.8) | |
| Tubular adenocarcinoma | 172 (75.8) | 60 (82.2) | |
| Mucinous adenocarcinoma | 20 (8.8) | 7 (9.6) | |
| Other | 18 (7.9) | 1 (1.4) | |
| Ascites | 0.066 | ||
| No | 207 (91.2) | 61 (83.6) | |
| Yes | 20 (8.8) | 12 (16.4) | |
| Tumor size (cm) | 0.053 | ||
| ≤5 | 144 (63.4) | 37 (50.7) | |
| >5 | 83 (36.6) | 36 (49.3) | |
| Tumor location | 0.185 | ||
| Colon | 98 (43.2) | 38 (52.1) | |
| Rectum | 129 (56.8) | 35 (47.9) | |
| Peritoneal metastasis | 0.011 | ||
| No | 224 (98.7) | 68 (93.2) | |
| Yes | 3 (1.3) | 5 (6.8) | |
| Liver metastasis | 0.10 | ||
| No | 216 (95.2) | 63 (86.3) | |
| Yes | 11 (4.8) | 10 (13.7) | |
| TNM stage | 0.000 | ||
| I | 40 (17.6) | 4 (5.5) | |
| II | 100 (44.1) | 25 (34.2) | |
| III | 76 (33.5) | 30 (41.1) | |
| IV | 11 (4.8) | 14 (19.2) | |
| Histological differentiation | 0.085 | ||
| High | 19 (8.4) | 4 (5.5) | |
| Moderate | 188 (82.8) | 56 (76.7) | |
| Poor | 20 (8.8) | 13 (17.8) | |
Data in parentheses represent percentage values.