Skip to main content
. Author manuscript; available in PMC: 2014 Sep 12.
Published in final edited form as: J Med Chem. 2013 Aug 23;56(17):6886–6900. doi: 10.1021/jm400711t

Table 2.

4-CR leading to the formation of the second-generation analogues based on the 7-deazaadenine skeleton.

graphic file with name nihms517620u2.jpg
7-deazaadenine Ar1 Ar2 % yield
23a graphic file with name nihms517620t19.jpg Ph 58
23b graphic file with name nihms517620t20.jpg Ph 66
23c Ph Ph 48
23d graphic file with name nihms517620t21.jpg Ph 85
23e graphic file with name nihms517620t22.jpg graphic file with name nihms517620t23.jpg 54
23f graphic file with name nihms517620t24.jpg Ph 72