Table 4.

4-CR leading to the formation of the second-generation analogues based on the 7-deazahypoxanthine skeleton.

7-deazahypoxanthine	Ar1	Ar2	% yield
25a	Ph	Ph	71
25b		Ph	68
25c		Ph	61
25d		Ph	54
25e		Ph	53
25f		Ph	60
25g		Ph	88
25h		Ph	61
25i		Ph	64
25j		Ph	37
25k		Ph	51
25l		Ph	74
25m		Ph	77
25n		Ph	26
25o		Ph	47
25p			56
25q			56
25r			60
25s			61
25t			54
25u	Ph		68
25v		Ph	71