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. Author manuscript; available in PMC: 2014 Sep 12.
Published in final edited form as: J Med Chem. 2013 Aug 23;56(17):6886–6900. doi: 10.1021/jm400711t

Table 5.

4-CR with concomitant debenzylation leading to the formation of hydroxyl-substituted 7-deazahypoxanthine analogues.

graphic file with name nihms517620u5.jpg
7-deazahypoxanthine Ar1 Ar2 % yield
25w Ph Ph 88
25x graphic file with name nihms517620t59.jpg graphic file with name nihms517620t60.jpg 70
25y graphic file with name nihms517620t61.jpg graphic file with name nihms517620t62.jpg 64
25z graphic file with name nihms517620t63.jpg graphic file with name nihms517620t64.jpg 71