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. 2013 Jul 23;1(5):887–893. doi: 10.3892/mco.2013.153

Table III.

Relationships between mRNA levels and clinical characteristics.

Characteristic Statistics BRCA1 TYMS STMN1 TOP2A PDGFR VEGFR2 KIT HER2
Gender χ2 3.042 7.846 0.255 5.702 1.318 0.255 1.771 0.008
P-value 0.081 0.005 0.614 0.017 0.251 0.614 0.183 0.927
Age (years) χ2 0.124 0.006 0.006 0.006 3.176 0.006 3.200 0.608
P-value 0.725 0.939 0.939 0.939 0.075 0.939 0.074 0.436
Stage χ2 1.455 1.769 4.989 3.949 0.626 9.081 10.277 8.388
P-value 0.693 0.622 0.173 0.267 0.890 0.028 0.016 0.039
Primary tumor χ2 4.832 1.482 4.314 3.665 3.829 6.149 10.267 1.799
P-value 0.185 0.686 0.230 0.300 0.281 0.105 0.016 0.615
Lymph nodes χ2 3.692 7.394 0.839 5.162 3.622 0.353 1.385 1.073
P-value 0.297 0.060 0.840 0.160 0.305 0.950 0.709 0.784
Distant metastasis χ2 0.036 0.095 0.036 0.653 0.328 7.222 1.709 4.183
P-value 0.849 0.758 0.849 0.419 0.567 0.007 0.191 0.041
Histological type χ2 16.481 8.074 1.831 5.713 1.075 1.075 3.255 6.618
P-value 0.000 0.004 0.176 0.017 0.300 0.300 0.071 0.010
Differentiation χ2 1.462 5.942 5.544 0.795 0.443 0.443 4.043 5.427
P-value 0.481 0.051 0.063 0.672 0.801 0.801 0.132 0.066
Smoking history χ2 6.867 5.888 0.268 8.106 4.988 0.507 1.357 0.085
P-value 0.009 0.015 0.605 0.004 0.026 0.476 0.244 0.771

Statistics were calculated by the χ2 test and the undetermined samples were not included. The cut-off point of the primary tumor was 3 cm. BRCA1, breast cancer 1; TYMS, thymidylate synthetase; STMN1, stathmin 1; TOP2A, topoisomerase II α; VEGFR2, vascular endothelial growth factor receptor 2; PDGFR, platelet-derived growth factor receptor; HER2, human epidermal growth factor receptor 2.