Table IV.
Correlations between mRNA levels and clinical characteristics.
Characteristic | Statistics | BRCA1 | TYMS | STMN1 | TOP2A | PDGFR | VEGFR2 | KIT | HER2 |
---|---|---|---|---|---|---|---|---|---|
Gender | r | 0.179 | 0.287 | 0.052 | 0.245 | −0.118 | 0.052 | −0.137 | −0.009 |
P-value | 0.083 | 0.005 | 0.618 | 0.017 | 0.256 | 0.618 | 0.187 | 0.928 | |
Age (years) | r | 0.036 | 0.008 | −0.008 | 0.008 | −0.171 | −0.008 | 0.184 | −0.080 |
P-value | 0.729 | 0.940 | 0.940 | 0.940 | 0.076 | 0.940 | 0.075 | 0.441 | |
Stage | ρ | −0.056 | 0.012 | −0.061 | 0.014 | 0.082 | 0.276 | −0.216 | 0.140 |
P-value | 0.595 | 0.912 | 0.567 | 0.896 | 0.442 | 0.008 | 0.040 | 0.186 | |
Primary tumor | ρ | −0.036 | 0.044 | 0.149 | 0.151 | −0.102 | −0.018 | −0.161 | −0.011 |
P-value | 0.738 | 0.681 | 0.164 | 0.159 | 0.340 | 0.864 | 0.132 | 0.921 | |
Lymph nodes | ρ | −0.023 | 0.220 | 0.042 | 0.197 | 0.060 | 0.043 | −0.111 | 0.075 |
P-value | 0.833 | 0.039 | 0.693 | 0.064 | 0.577 | 0.687 | 0.300 | 0.483 | |
Distant metastasis | r | 0.020 | 0.033 | 0.020 | 0.086 | 0.061 | 0.285 | −0.139 | 0.217 |
P-value | 0.851 | 0.761 | 0.851 | 0.425 | 0.572 | 0.007 | 0.195 | 0.041 | |
Histological type | r | −0.419 | −0.293 | −0.140 | −0.247 | 0.107 | 0.107 | −0.186 | 0.265 |
P-value | 0.000 | 0.004 | 0.180 | 0.017 | 0.305 | 0.305 | 0.073 | 0.010 | |
Differentiation | ρ | −0.123 | −0.264 | −0.260 | −0.098 | −0.069 | 0.069 | 0.144 | 0.115 |
P-value | 0.272 | 0.016 | 0.018 | 0.383 | 0.540 | 0.540 | 0.197 | 0.304 | |
Smoking history | r | 0.275 | 0.254 | 0.054 | 0.298 | −0.234 | 0.075 | −0.122 | −0.031 |
P-value | 0.009 | 0.015 | 0.609 | 0.004 | 0.026 | 0.482 | 0.249 | 0.774 |
The undetermined samples were not included in statistics. The cut-off point of the primary tumor was 3 cm. r, Pearson’s product-moment correlation coefficient; ρ, Spearman’s rank correlation coefficient; BRCA1, breast cancer 1; TYMS, thymidylate synthetase; STMN1, stathmin 1; TOP2A, topoisomerase II α; PDGFR, platelet-derived growth factor receptor; VEGFR2, vascular endothelial growth factor receptor 2; HER2, human epidermal growth factor receptor 2.