Table 2.
Biochemical parameters and histopathological scores in all groups (mean ± SD).
| Parameters | Sh (n = 6) | Sh + EP (n = 6) | S/C (n = 9) | S/C + EP (n = 9) |
|---|---|---|---|---|
| MPO (ng/mL) | 81.82 ± 34.21 | 96.91 ± 49.32 | 383.85 ± 38.19a,b | 198.33 ± 69.16a,b,c |
| MDA (nmol/mL) | 1.42 ± 0.43 | 1.45 ± 0.34 | 2.95 ± 1.45a,b | 1.96 ± 0.61a,b,c |
| TNFα (pg/mL) | 151.63 ± 30.64 | 147.52 ± 16.14 | 262.71 ± 18.24a,b | 188.76 ± 56.55a,b,c |
| IL-6 (pg/mL) | 164.62 ± 16.18 | 157.98 ± 19.93 | 196.53 ± 52.22 | 183.98 ± 56.75 |
| IMA (ABSU) | 0.42 ± 0.3 | 0.32 ± 0.21 | 0.84 ± 0.43a,b | 0.74 ± 0.22a,b |
| Lung MDA (nmol/g) | 454.29 ± 35.2 | 461.63 ± 51.26 | 522.5 ± 81.12a,b | 499.14 ± 43.2a,b,c |
| Lung MPO (ng/mL) | 5636.77 ± 404.7 | 5894.49 ± 971.17 | 6541.1 ± 613.4a,b | 6019.12 ± 394.4a,c |
| W/D weight ratio | 2.28 ± 0.18 | 2.21 ± 0.08 | 5.55 ± 0.45a,b | 3.77 ± 0.74a,b,c |
| Histopathological score | 0.5 ± 0.5 | 0.5 ± 0.4 | 2.66 ± 0.7a,b | 1.44 ± 0.72a,b,c |
Note: Sh: sham; EP: ethyl pyruvate; S/C: shock/clamp; MDA: malondialdehyde; MPO: myeloperoxidase; TNFα: tumor necrosis factor alpha; IL-6: interleukin-6; IMA: ischemia modified albumin; W/D ratio: wet/dry ratio.
a P < 0.016 versus Sh.
b P < 0.016 versus Sh + EP.
c P < 0.016 versus S/C.