Table 1. Composition of the liquisolid compacts .
Drug in conc of PEG 200 | Batch | R value | Drug (mg) | Liquid load (Lf) | Avicel PH 102 (mg) | Aerosil (mg) | SSG (mg) | PEG 200 (mg) | Unit dose (mg) |
F1 | 10 | 5 | 0.326 | 102.24 | 10.22 | 7.28 | 28.33 | 153.07 | |
15% | F2 | 20 | 5 | 0.163 | 204 | 10.20 | 12.37 | 28.33 | 259.9 |
F3 | 30 | 5 | 0.109 | 305.77 | 10.19 | 17.46 | 28.33 | 366.75 | |
20% | F4 | 10 | 5 | 0.326 | 76.68 | 7.66 | 5.44 | 20 | 114.78 |
F5 | 20 | 5 | 0.163 | 218.57 | 10.92 | 12.72 | 20 | 367.21 | |
F6 | 30 | 5 | 0.109 | 229.35 | 7.645 | 13.09 | 20 | 275.08 | |
25% | F7 | 10 | 5 | 0.326 | 61.34 | 6.13 | 4.37 | 15 | 191.84 |
F8 | 20 | 5 | 0.163 | 122.69 | 6.13 | 7.44 | 15 | 156.231 | |
F9 | 30 | 5 | 0.109 | 183.48 | 6.11 | 10.47 | 15 | 220.06 |