Figure 5.
Simulations of immune-mediated tumour dormancy assuming the three fits for decay are applied to the recruitment potential while the predation strength is constant. Recruitment is assumed to decay according to fit 1 in (a), fit 2 in (b) and fit 3 in (c) with the initial value of μ = 10−3, and the timescale of the decay determined by the fit. Cancer–immune phase portraits for each fit are shown in (d–f). Note that as recruitment decays, even though predation strength is strong, the immune population cannot maintain the dormant state. The escape time for each fit is indicated in the corresponding plot.