Table 1.

Model parameters and variable definitions. Variables can change during a simulation. Numerical values are parameters fixed for the duration of a simulation. Range values are deterministically calculated from other variables/parameters.

symbol	description	value	unit
R	resource concentration	variable	μg ml−1
Ni	density of host strain i	variable	cells ml−1
Vj	density of phage strain j	variable	virions ml−1
Ninit	initial host density	4.6×104	cells ml−1
Vinit	initial phage density	8.1×105	virions ml−1
ω	chemostat dilution rate	0.0033	min−1
R0	resource supply concentration	2.2	μg ml−1
ɛ	resource conversion rate	2.6×10−6	μg cell−1
γ	maximum resource uptake rate	0.0123	μg min−1
K	half-saturation constant	4	μg ml−1
δi	growth scaling for host hi	range [δmin,δmax]	scalar
δmin	minimum growth scaling factor	0.8	scalar
δmax	maximum growth scaling factor	1.2	scalar
ϕ	maximum adsorption rate	0.104×10−8	ml(min virion)−1
θij	adsorption scaling for vj on hi	range [0,ϕ]	scalar
β	burst size	71	virions cell−1
hi	genotype of bacteria i	range [0,1]	scalar
vj	genotype of phage j	range [0,1]	scalar
	resistance phenotype of bacteria i	range [0,1]	scalar
	infection phenotype of phage j	range [0,1]	scalar
hinit	initial bacteria genotype	0.2	scalar
vinit	initial phage genotype	0.2	scalar
S	specificity of phage	100	scalar
μN	host mutation rate	10−6	cell−1
μV	phage mutation rate	10−5	virion−1
σN	s.d. of host mutation range	0.01	scalar
σV	s.d. of phage mutation range	0.01	scalar
MN	bacterial mutation size	random variable	scalar
MV	phage mutation size	random variable	scalar
Δt	integration time step	10	min
T	simulation duration	5×107	min
ρ	resolution of genotype diversity	0.001	scalar
L	chemostat volume	1	ml