The IOP of experimental (Exp) and fellow control (Ctrl) eyes under general anesthesia at baseline immediately before cannulation (BL), at 0 to 5 minutes and 6 to 20 minutes after cannula removal, and at the 1-day, 2-day, 3-day, 7-day, and 14-day follow-up. Data are shown for group 1 (n = 15) and group 2 (n = 4), which both had IOP elevation to 50 mm Hg for 8 hours, and for group 3 (n = 4, sham), which had IOP held at 15 mm Hg for 8 hours. The IOP in the experimental eyes decreased immediately after cannula removal but recovered relative to baseline and fellow control by the 1-day follow-up. Error bars = SEM. *P < 0.05 in experimental eyes compared with fellow control at that time point. §P < 0.05 in experimental eyes compared with baseline (Bonferroni post hoc test).