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. Author manuscript; available in PMC: 2014 Feb 6.
Published in final edited form as: Leukemia. 2012 Mar 30;26(10):2286–2296. doi: 10.1038/leu.2012.91

Figure 3. CD147 expression levels are increased on MM sequential patient PCs samples with progressive disease.

Figure 3

Surface expression levels of CD147 on primary CD138+ primary MM PCs (gray histogram) versus isotype-matched control (black histogram). A) CD147 levels on primary CD138+ primary MM PCs from a MM patient (Pt. 1) with asymptomatic but progressive disease (ΔMFI= 4.9) B) and eight months later (ΔMFI =30.2). C) CD147 levels on CD138+ cells from a MM patient (Pt. 2) at time of autologous stem cell transplant (ΔMFI =1.0) D) and 100 days post-PBSCT (ΔMFI =4.6), who eventually progressed to relapse E) 1 yr post-PBSCT (ΔMFI =38). F) CD147 levels on primary CD138+ primary MM PCs from an asymptomatic MM patient placed on initial treatment (Pt. 3)(ΔMFI =5) and CD147 levels measured 7 months post-treatment initiation G) (ΔMFI =5.5) and 11 months post-treatment initiation, at which time a very good partial response with concerns of progression were noted H) (ΔMFI =23.8).