Table 2.
Effect of buspirone on lipid parameters.
| Lipid parameters | CON | COB | DIC | DIB |
|---|---|---|---|---|
| Serum triglyceride (mg/dL) | 43.03 ± 3.51 | 43.72 ± 5.83 | 193.85 ± 14.47* | 134.73 ± 3.03 |
| Total serum cholesterol (mg/dL) | 71.32 ± 3.00 | 73.07 ± 4.85 | 93.63 ± 2.40* | 83.57 ± 3.11 |
| Serum VLDL-C (mg/dL) | 8.89 ± 0.67 | 8.74 ± 1.17 | 38.77 ± 2.89* | 26.95 ± 0.61 |
| Serum LDL-C (mg/dL) | 24.69 ± 1.36 | 26.79 ± 3.79 | 38.45 ± 1.92* | 29.53 ± 0.83 |
| Serum HDL-C (mg/dL) | 29.79 ± 3.07 | 27.02 ± 2.00 | 13.21 ± 1.26* | 18.62 ± 2.33 |
| Log TG/HDL ratio | 0.0069 ± 0.0006 | 0.0084 ± 0.0008 | 0.02806 ± 0.0023 | 0.0188 ± 0.0014 |
*Significantly different from normal control (P < 0.05).
#Significantly different from diabetic control (P < 0.05).
Values are expressed as mean ± SEM of 6 experiments.
CON: normal control, COB: control treated with buspirone, DIC: diabetic control, and DIB: diabetic treated with buspirone.