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. 2013 Dec 3;24(2):204–217. doi: 10.1038/cr.2013.158

Figure 3.

Figure 3

Targeted downregulation of MPZL1 attenuates HCC cell migration. (A) The detection of the relative protein levels of MPZL1 in six HCC cell lines by immunoblotting. Arrows denote the position of MPZL1. (B) The detection of shRNA-mediated knockdown of MPZL1 in SK-HEP-1 and Li-7 cells by immunoblotting. (C) A representative result of the CCK-8 assays for the effects of MPZL1 knockdown on the in vitro proliferation of SK-HEP-1 and Li-7 cells. (D, E) Representative results of the transwell assays for the effects of MPZL1 knockdown on the in vitro migratory and invasive abilities of SK-HEP-1 and Li-7 cells, respectively. Statistical analysis of differences between groups was performed by unpaired Student's t-test. The results are shown as the mean ± s.e.m, **P < 0.01; ***P < 0.001.