Table 1.
Description of cognitive function outcome measures.
| Task | Acronym | Outcome measure | Description |
|---|---|---|---|
| Attention | |||
| Big/little circle | BLC | Mean correct latency (ms) | Speed of response showing how quickly participant touched the correct stimulus after it was displayed on the screen |
| Mean percent correct (%) | Percent of total correct responses | ||
| Reaction time | RTI | Five-choice movement time (ms) | Time taken to touch correct stimulus after release of the press pad |
| Five-choice reaction time (ms) | Speed with which participant releases press pad in response to stimulus at one of five locations | ||
|
| |||
| Visual Memory | |||
| Delayed matching to sample | DMS | Percent correct (all delays) (%) | Percent of correct stimulus selection after stimulus was hidden at delays of 0 s, 4 s, and 12 s |
| Percent correct (simultaneous) (%) | Percent of correct stimulus selection during simultaneous presentation of target stimulus and distractors | ||
| Mean correct latency (all delays) | Average speed of response where correct stimulus was selected in trials in which stimulus was hidden at delays of 0 s, 4 s, and 12 s | ||
| Mean correct latency (simultaneous) | Average speed of response where correct stimulus was selected in trials with simultaneous presentation of target stimulus and distractors | ||
| Paired associates learning | PAL | Mean trials to success | Total number of trials required to correctly locate patterns/number of successfully completed stages |
| Total errors (adjusted) | Total number of errors with adjustment for each stage not attempted due to previous failure | ||
| Total trials (adjusted) | Total number of presentations required to correctly locate patterns in all stages | ||
| Pattern recognition memory | PRM | Percent correct | Percent correct responses |
| Mean correct latency (ms) | Mean time to respond correctly | ||
|
| |||
| Executive Function/Set-Shifting and Working Memory | |||
| Intra/extradimensional set-shifting | IED | Stages completed | Number of stages completed out of nine possible |
| Pre-ED errors | Number of errors prior to the extradimensional shift | ||
| EDS errors | Errors made in the extradimensional stage | ||
| Spatial working memory | SWM | Strategy | Number of times participant begins a search with the same box for 6- and 8-box problems |
| Between errors (4, 6, and 8 boxes) | Times the participant revisits a box in which a token was previously found; errors calculated for 4-, 6-, and 8-box trials | ||
|
| |||
| Executive Function/Spatial Planning | |||
| Stockings of Cambridge | SOC | Problems solved in minimum moves | Number of times participant successfully completed a test problem in the minimum possible number of moves |
| Mean initial thinking time (2, 3, 4, and 5 moves) | Time taken to plan a problem solution for trials requiring 2, 3, 4, and 5 moves | ||
| Mean subsequent thinking time (2, 3, 4, and 5 moves) | Speed of movement after the initial move has been made for trials requiring 2, 3, 4, and 5 moves | ||
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| |||
| Decision Making and Response Control | |||
| Affective go/no-go | AGN | Mean correct latency | Mean time taken to respond correctly to each target word stimulus in all assessed blocks. |
| Total omissions | Total number of missed responses to targets in all assessed blocks | ||
| Total commissions | Total number of responses to distractors in all assessed blocks | ||
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| |||
| Verbal Learning and Memory | |||
| Verbal recognition memory | VRM | Immediate free recall total correct | Total number of words correctly recalled immediately following presentation of word list |
| Immediate free recall total novel words | Total number of words recalled immediately following presentation of word list that were not a part of the list | ||
| Immediate free recall total perseverations | Total number of times a previously correctly recalled word is repeated immediately following presentation of word | ||
| Immediate recognition total correct | Total number of words correctly recalled during presentation of word list that includes correct targets and distractors | ||
| Immediate recognition total false positives | Total number of distractors endorsed as correct responses during presentation of word list that includes correct targets and distracters | ||
| Delayed recognition total correct | Total number of words correctly recalled during presentation of word list that includes correct targets and distractors following 20 min delay from original presentation of word list | ||
| Delayed recognition total false positives | Total number of distractors endorsed as correct responses during presentation of word list that includes correct targets and distractors following 20 min delay from original presentation of word list | ||