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. Author manuscript; available in PMC: 2014 Feb 6.
Published in final edited form as: Curr Drug Targets. 2010 Jun;11(6):682–698. doi: 10.2174/138945010791170851

Fig. 4.

Fig. 4

Schematic representation of ligand induced activation of EGFR(s) signalling pathway. Ligand binding to the receptor results in dimerization and auto-/trans-phosphorylation that initiate the signaling cascade.