Table IV.
Genotype distributions of the rs2294008 polymorphism among different subtypes of gastric cancer from the Tibet, Hui and Han nationalities.
| Genotype | Controls, n (%) | Intestinal cases | Diffuse cases | ||||
|---|---|---|---|---|---|---|---|
|
|
|
||||||
| Cases | OR (95% CI)a | P-value | Cases | OR (95% CI)a | P-value | ||
| Tibet | |||||||
| CC | 154 (53.85) | 69 (45.10) | 1 | 24 (36.36) | 1 | ||
| CT | 113 (39.51) | 69 (45.10) | 1.36 (0.90–2.06) | 0.142 | 34 (51.52) | 1.93 (1.09–3.44) | 0.025 |
| TT | 19 (6.64) | 15 (9.80) | 1.76 (0.85–3.69) | 0.129 | 8 (12.12) | 2.69 (1.06–6.84) | 0.038 |
| Hui | |||||||
| CC | 129 (40.95) | 45 (28.85) | 1 | 27 (35.06) | 1 | ||
| CT | 145 (46.03) | 81 (51.92) | 1.60 (1.04–2.47) | 0.034 | 31 (40.26) | 1.02 (0.58–1.18) | 0.941 |
| TT | 41 (13.02) | 30 (19.23) | 2.10 (1.17–375) | 0.012 | 19 (24.68) | 2.21 (1.12–4.38) | 0.023 |
| Han | |||||||
| CC | 182 (52.00) | 82 (43.62) | 1 | 0.005 | 28 (36.36) | 1.79 (0.85–3.77) | 0.126 |
| CT | 143 (40.86) | 89 (47.34) | 1.38 (0.95–2.00) | 0.088 | 38 (49.35) | 1.73 (1.01–2.95) | 0.045 |
| TT | 25 (7.14) | 17 (9.04) | 1.51 (0.77–2.95) | 0.228 | 11 (14.29) | 2.86 (1.27–6.46) | 0.011 |
a
Adjusted for age, gender and smoking status.